Minimises operating room time with each cannula insertion and fixation circa 10-minutes. Reduces infusion procedure time with simultaneous infusions of up to eight cannulas per patient on the ward. Bedside removal of cannulas.
Effective
Our innovative micro-fluted cannula with an adjustable step-length enables distribution to be shaped to match individual treatment volumes.
Scaleable
Implantation using widely available stereotactic frames and robots. Cost-effective procedures are driven by simultaneous infusions in awake patients enabling effective use of the OR and staff.
CED compared to other approaches
Can target specific brain & spine anatomy
Doesn't risk off-target side-effects including hepatotoxicity
Homogeneous distribution of therapeutics
High spinal cord and brain transduction
Penetration of CNS not limited by blood-brain-barrier
Not affected by circulating neutralising antibodies
Does not require high infused titres to achieve CNS penetration
Reduced risk of DRG toxicity
The Neurochase CED system
The Blood-Brain Barrier prevents many therapeutics accessing the brain. Even if overcome, many therapies require effective doses to be confined to specific brain targets. Existing methods for one-time direct administration of therapies to targeted areas deep within the brain are complex, requiring expensive equipment and long procedure times. Additionally, many available in-dwelling catheters for treatments requiring chronic infusions (which?) are suboptimal. The Neurochase CED medical device is designed to revolutionise how neurodegenerative diseases are treated. We aim to significantly reduce procedure times and improve the patient experience with our fast, accurate, and highly-scalable procedure for both acute and chronic infusions.* Neurochase is the leading global biotechnology company focused exclusively on innovative devices and consulting services for CNS drug delivery.
*Currently for investigational use only. Not approved for clinical use in any geography.
Animation of how a catheter is inserted into a specific target area of the brain using the Neurochase system
The Power of Mindfulness:
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